Gastric

• Helicobacter pylori
• Pepsinogen I and II
• Gastrin
• Chromogranin A
• Somatostatin

Lipid metabolism

• Free fatty acids and phospholipid B
• Apolipoprotein A-1, B, E and C-III
• Adiponectin
• Leptin
• Ghrelin

Bone

• Bone-specific alkaline phosphatase
• Growth hormone
• Intact parathyroid hormone
• Total MMP-9
• Osteocalcin

Platelet function and coagulation

• 11-dehydro thromboxane B2 in urine
• 2, 3-dinor-6-keto prostaglandin F1α
• Factor X PT
• Heparin activity (HEP LMW)
• Plasmin inhibitor
• Platelet aggregation with a variety of stimulants
• PFA 100
• Cone and plate analyser

Renal

• Cystatin C
• Retinol-binding protein (RBP 4)
• Urine Beta NAG
• Renin and aldosterone
• Corticosterone

Diabetic

• Insulin and C-peptide
• Glucagon

Cardiac

• Troponin I
• CK-MB
• Myoglobin
• BNP

Reproductive

• Inhibin B
• Sex hormone-binding globulin (SHBG)
• DHEA and DHEA-SO4

Inflammation/immunity

• Gated auto fluorescence forward scatter (GAFs) assay
• Platelet activation markers & reticulated platelets
• Neutrophil CD11b and shape change
• Neopterin
• Surfactant protein D (SP-D)
• Myeloperoxidase (MPO)

Cytokine

• Inflammatory
• Chemokines
• Interferons
• Interleukins
• Lymphokines
• Tumour necrosis factors

Cell level biomarkers

We have multicolour flow cytometry capabilities to detect differential expression of cell surface markers and cytokine secretion profiles. We can validate / characterise / accommodate method transfers to determine the phenotype, receptor occupancy, and/or Ab expression levels of cells and their subtypes.

Examples of assays we’ve done:

• enumeration of lymphocyte subsets
• neutrophil CD11b and neutrophil shape change
• platelet activation markers & reticulated platelets
• stem cell enumeration
• expression of T cell surface receptor Programmed cell death 1 (PD-1)

Cell stimulation

• PMA and ionomycin
• KLH
• LPS
• … etc

…and many more!